HMGB1 in health and disease
R Kang, R Chen, Q Zhang, W Hou, S Wu, L Cao… - Molecular aspects of …, 2014 - Elsevier
Complex genetic and physiological variations as well as environmental factors that drive
emergence of chromosomal instability, development of unscheduled cell death, skewed
differentiation, and altered metabolism are central to the pathogenesis of human diseases
and disorders. Understanding the molecular bases for these processes is important for the
development of new diagnostic biomarkers, and for identifying new therapeutic targets. In
1973, a group of non-histone nuclear proteins with high electrophoretic mobility was …
emergence of chromosomal instability, development of unscheduled cell death, skewed
differentiation, and altered metabolism are central to the pathogenesis of human diseases
and disorders. Understanding the molecular bases for these processes is important for the
development of new diagnostic biomarkers, and for identifying new therapeutic targets. In
1973, a group of non-histone nuclear proteins with high electrophoretic mobility was …
