Ferroptosis is a regulated iron-dependent cell death mechanism accompanied by the
accumulation of peroxidized phospholipids, particularly phosphatidylethanolamine, in the
cell. It occurs due to the disbalance between production and elimination of oxidized
phospholipids in response to ferroptotic stimuli. A growing body of recent studies indicates
that ferroptosis is involved in the pathogenesis of various human diseases leading to
organ/tissue abnormalities. Because of their central role in ATP synthesis, ROS production …