Plasma leptin: associations with metabolic, inflammatory and haemostatic risk factors for cardiovascular disease
SG Wannamethee, J Tchernova, P Whincup… - Atherosclerosis, 2007 - Elsevier
BACKGROUND AND AIM: Leptin, an adipocyte-derived protein, regulating food intake and
metabolism has been implicated in the development of coronary heart disease. We have
examined the relationship between leptin and vascular risk factors including insulin
resistance, metabolic, inflammatory and haemostatic risk factors. METHODS AND
RESULTS: The study was carried out in 3640 non-diabetic men aged 60–79 years drawn
from general practices in 24 British towns and who were not on warfarin. Leptin was strongly …
metabolism has been implicated in the development of coronary heart disease. We have
examined the relationship between leptin and vascular risk factors including insulin
resistance, metabolic, inflammatory and haemostatic risk factors. METHODS AND
RESULTS: The study was carried out in 3640 non-diabetic men aged 60–79 years drawn
from general practices in 24 British towns and who were not on warfarin. Leptin was strongly …
