[HTML][HTML] Tissue factor‐bearing microparticles and inflammation: A potential mechanism for the development of venous thromboembolism in cancer
K Date, C Ettelaie, A Maraveyas - Journal of Thrombosis and Haemostasis, 2017 - Elsevier
Cancer is associated with an increased risk of venous thromboembolism (VTE); the exact
mechanisms for the induction of VTE remain to be fully elucidated, but it is widely
acknowledged that tissue factor (TF)‐bearing microparticles (TF‐MPs) may play a significant
role. However, TF‐MPs have yet to be accepted as a genuine biomarker for cancer‐
associated VTE, as the presence of elevated TF‐MP levels is not always accompanied by
thrombosis; interestingly, in certain cases, particularly in pancreatic cancer, VTE seems to be …
mechanisms for the induction of VTE remain to be fully elucidated, but it is widely
acknowledged that tissue factor (TF)‐bearing microparticles (TF‐MPs) may play a significant
role. However, TF‐MPs have yet to be accepted as a genuine biomarker for cancer‐
associated VTE, as the presence of elevated TF‐MP levels is not always accompanied by
thrombosis; interestingly, in certain cases, particularly in pancreatic cancer, VTE seems to be …
