Plasma tissue factor may be predictive of venous thromboembolism in pancreatic cancer
AA Khorana, CW Francis, KE Menzies… - Journal of Thrombosis …, 2008 - jthjournal.org
Pancreatic cancer is the fourth leading cause of cancer death in the US [1]. It is frequently
complicated by venous thromboembolism (VTE), with published incidence rates varying
from 17% to 57%[2]. VTE can directly contribute to mortality, and has been associated with
poor outcomes in pancreatic cancer [3]. Tissue factor (TF) is the principal physiologic initiator
of coagulation and is commonly expressed in a variety of cancers. In pancreatic cancer, high
grade TF expression is an adverse prognostic factor [4]. We recently published findings …
complicated by venous thromboembolism (VTE), with published incidence rates varying
from 17% to 57%[2]. VTE can directly contribute to mortality, and has been associated with
poor outcomes in pancreatic cancer [3]. Tissue factor (TF) is the principal physiologic initiator
of coagulation and is commonly expressed in a variety of cancers. In pancreatic cancer, high
grade TF expression is an adverse prognostic factor [4]. We recently published findings …
